Principal Investigator

Daniel Huddleston, MD

Dr. Huddleston is Assistant Professor of Neurology at Emory University, School of Medicine, since 2016. As a physician-scientist, he sees patients in the Emory Movement Disorders Clinic and conducts translational MRI research for neurodegenerative diseases. He received his medical degree from Columbia University, College of Physicians and Surgeons, in 2006. He continued his training with a residency in neurology at Columbia’s Neurological Institute of New York, followed by a fellowship in movement disorders neurology at the Emory University Movement Disorders Clinic.


Dr. Huddleston’s current research involves the development and application of MRI methods to study Parkinson’s disease and related neurodegenerative disorders. He uses novel neuromelanin-sensitive and multicontrast MRI approaches to study neurodegeneration in the substantia nigra and the locus coeruleus. Overall, his goal is to synthesize these innovative imaging methods with clinical and molecular data using machine learning to develop multimodal disease signatures for clinical and translational applications. Funding from the NIH, private foundations and private donors have supported his work. Dr. Huddleston is the Emory site principal investigator for 2 national consortia, one being the Emory Lewy Body Dementia Association Research Center of Excellence, and the other being the North American Prodromal Synucleinopathy Consortium. In 2018, he received the Young Faculty Award at the AAT-AD/PD Annual Meeting in Torino, Italy.

Key Scientific Collaborators

MRI Physics and Image Processing

Xiaoping Hu, PhD

Chair of Bioengineering

Director, Center for Advanced Neuroimaging

University of California Riverside

Jason Langley, PhD

MRI Physicist

Center for Advanced Neuroimaging

University of California Riverside

Neural Systems Imaging

Bruce Crosson, PhD


Deptartment of Neurology

Emory University

Biomedical Informatics

David Gutman, MD, PhD

Associate Professor

Dept. of Biomedical Informatics

 Emory University

Machine Learning

Babak Mahmoudi, PhD

Assistant Professor

Dept. of Biomedical Informatics, Emory University

Dept. of Biomedical Engineering, Georgia Tech


Dean Jones, PhD

Director, Clinical Biomarkers Lab

Professor, Depts. of Medicine and Biochemistry

Emory University

Associate Professor, Dept. of Medicine

Emory University

Research Health Scientist, Atlanta VA

Madeleine Hackney, PhD

Exercise Interventions

Lab Team Members

Kristy Hwang, MD

Neurology Resident

Department of Neurology

Emory University

Kelsey Tucker

Clinical Research Coordinator

Depts. of Neurology and Medicine--Geriatrics

Emory University

Nithin Kurra, MPH

Research Specialist

Department of Neurology

Emory University