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Principal Investigator

Dr. Dan Huddleston

Daniel Huddleston, MD

Dr. Huddleston is Assistant Professor of Neurology at Emory University, School of Medicine, since 2016. As a physician-scientist, he sees patients in the Emory Movement Disorders Clinic and conducts translational MRI research for neurodegenerative diseases. He received his medical degree from Columbia University, College of Physicians and Surgeons, in 2006. He continued his training with a residency in neurology at Columbia’s Neurological Institute of New York, followed by a fellowship in movement disorders neurology at the Emory University Movement Disorders Clinic.


Dr. Huddleston’s current research involves the development and application of MRI methods to study Parkinson’s disease and related neurodegenerative disorders. He uses novel neuromelanin-sensitive and multicontrast MRI approaches to study neurodegeneration in the substantia nigra and the locus coeruleus. Overall, his goal is to synthesize these innovative imaging methods with clinical and molecular data using machine learning to develop multimodal disease signatures for clinical and translational applications. Funding from the NIH, private foundations and private donors have supported his work. Dr. Huddleston is the Emory site principal investigator for 2 national consortia, one being the Emory Lewy Body Dementia Association Research Center of Excellence, and the other being the North American Prodromal Synucleinopathy Consortium. In 2018, he received the Young Faculty Award at the AAT-AD/PD Annual Meeting in Torino, Italy.

Key Scientific Collaborators

MRI Physics and Image Processing

Dr. Xiaoping Hu

Xiaoping Hu, PhD

Chair of Bioengineering

Director, Center for Advanced Neuroimaging

University of California Riverside

Brain MRI

Jason Langley, PhD

MRI Physicist

Center for Advanced Neuroimaging

University of California Riverside

Neural Systems Imaging

Dr. Bruce Crosson

Bruce Crosson, PhD


Deptartment of Neurology

Emory University

Biomedical Informatics

Dr. David Gutman

David Gutman, MD, PhD

Associate Professor

Dept. of Biomedical Informatics

 Emory University

Machine Learning

Dr. Babak Mahmoudi

Babak Mahmoudi, PhD

Assistant Professor

Dept. of Biomedical Informatics, Emory University

Dept. of Biomedical Engineering, Georgia Tech


Dr. Dean Jones

Dean Jones, PhD

Director, Clinical Biomarkers Lab

Professor, Depts. of Medicine and Biochemistry

Emory University

Associate Professor, Dept. of Medicine

Emory University

Research Health Scientist, Atlanta VA

Madeleine Hackney, PhD

Dr. Madeleine Hackney

Exercise Interventions

Lab Team Members


Paul Beach, DO, PhD

Autonomic Fellow

Department of Neurology

Beth Israel Deaconess Medical Center


Adjunct Assistant Professor

Department of Neurology

Emory University


Richa Tripathi, MD

Assistant Professor

Department of Neurology

Movement Disorders Division

Emory University


Kelsey Tucker, CCRC

Lab Manager

Department of Neurology

Emory University


Amanda Goodwin, MA

Clinical Research Coordinator I

Department of Neurology

Emory University

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