Job Opportunities

Post Doctoral Fellow

We are currently seeking 1-2 postdoctoral fellows to work in the lab. Ideal candidates will have a background which includes image processing and strong data analysis skills. Previous experience using FSL, Freesurfer or other image processing packages, as well as MATLAB, will be useful. Python coding skills will also be useful. A strong interest in neuroscience applications for MRI and multimodal strategies is required. Qualified candidates will have excellent scientific writing ability and strong oral communication skills. They must also be able to work effectively and collegially with colleagues. This position will provide opportunity for educational growth in the application of novel and advanced MRI technologies to the study of parkinsonian diseases.

 

The postdoctoral fellow will be involved in the development and application of an image processing pipeline that Dr. Huddleston is developing with collaborators in MRI physics/bioengineering and machine learning.


The postdoctoral fellow will have a number of impactful educational opportunities with Dr. Huddleston, and through frequent interactions with collaborators. His research approach involves the use of pulse sequences sensitive to disease-relevant tissue characteristics in ROIs implicated in pathogenesis. His laboratory has developed novel pulse sequences and image processing tools, as well as automated pipelines to carry out this work. Dr. Huddleston and his collaborators are recognized leaders in the field of neuromelanin-sensitive MRI. Machine learning tools are applied in the context of hypothesis-directed biological questions. We collect biofluids at study visits and collaborate with a metabolomics laboratory at Emory to develop multimodal disease signatures. We are also currently working with neurobiology collaborators to develop a new MRI-monitored model for Parkinson’s disease.

 

The Parkinsonism Neuroimaging Laboratory at Emory University, led by Dr. Huddleston, focuses on the development and application of MRI methods to study Parkinson’s disease and related neurodegenerative disorders. The lab uses novel neuromelanin-sensitive and multicontrast MRI methods to study neurodegeneration in the substantia nigra, locus coeruleus and related neural systems. An overarching goal of this work is to develop MRI tools to assist the early detection and differential diagnosis of parkinsonian disorders and to make clinical trials for these disorders more successful.

 

We take an interdisciplinary approach to combine MRI technologies with other data types (clinical assessments, neurocognitive testing, metabolomics, other molecular markers) to discover and validate new disease markers and signatures. To accomplish this, Dr. Huddleston's lab works closely with technical experts in MRI physics, image processing, machine learning, metabolomics, neurobiology and biomedical informatics. Dr. Huddleston's background in movement disorders neurology, Parkinson’s disease biology, and MRI methods allows us to investigate complex aspects of disease mechanisms, with the ultimate goal of improving patient care.

We have conducted human studies since 2010, and we have completed >340 MRI study visits. This work has led to an extensive database and the identification of an array of candidate MRI markers for prodromal and symptomatic Parkinson’s disease. We have an immediate need to produce manuscripts reporting existing findings from our ongoing studies. The overarching goal of this research program is to develop biomarker tools, therapeutic targets and new therapies to treat and prevent Parkinson’s disease, dementia with Lewy bodies, multiple system atrophy, progressive supranuclear palsy and related conditions.

Please email resume and cover letter to ktucke3@emory.edu to be considered.

Official Emory Job Listing can be found here.

Clinical Research Coordinator I

We are currently seeking an additional Clinical Research Coordinator I (CRCI) to work in the lab. The CRCI is a specialized research professional who will work under the direction of the Principal Investigator. The CRCI supports, facilitates, and coordinates daily research activities. Ideal candidates will have strong organizational, managerial and interpersonal skills and be both proactive and self-motivated. An interest in working with older adults with Parkinson’s disease and other neurodegenerative disorders who may have some cognitive impairment is required. Qualified candidates will have excellent oral communication skills, and ability to carry out data collection and management conscientiously. They must be able to work effectively and collegially with colleagues and be willing to learn and teach others. Meticulous attention to detail is required.

 

CRCI handles all administrative duties generally associated with the conduct of clinical research, including screening, recruitment, and scheduling of patients with Parkinson’s disease and related disorders. Recruitment will involve a detailed chart review process to screen research candidates, attending a consensus conference with qualified neurologists and investigators, and maintaining detailed records of recruitment decisions and outcomes. Recruitment will take place via email and telephone conversations with potential candidates. CRCI will schedule all portions of study visits, including MRI scans, DaTScans, lumbar punctures, blood draws, and clinical interviews and exams. CRCI will guard patient healthcare information and records meticulously and in accordance with all university and federal regulations.

 

CRCI will be able to independently carry out data collection at study visits, including taking vital signs, collecting blood samples, and administering comprehensive cognitive testing. Prior experience with cognitive testing and clinical research data collection is preferred. CRCI must be willing to learn proper administration of cognitive tests, motor tests and other assessments, and be willing to learn phlebotomy to collect blood specimens. CRCI conducts the informed consent process and discussion with research participants, including answering any questions relating to the study. CRCI will also be required to accompany study participants to various components of their visits, including MRI scans at Emory University Hospital. CRCI will maintain study data and enter data in a timely manner into a centralized database using SPSS and REDCap.

 

CRCI will maintain necessary administrative and ethics board documentation, including management of Institutional Review Board protocols and amendments under the supervision of the Principal Investigator. Manages scheduled tasks, including annual continuing review of protocols. Assists with quality assurance and tracks regulatory submissions. Performs related approved responsibilities as required.

Master’s in Public Health, another advanced degree in the realm of biomedicine or experience in clinical research of at least 2 years is preferred. Minimum requirements are below. For those with appropriate background, there will be opportunities to participate in statistical analysis and other relevant scientific activities. Where appropriate there will be opportunities to participate in drafting and editing scholarly abstracts and manuscripts, with potential for authorship roles.

Please email resume and cover letter to ktucke3@emory.edu to be considered.

Official Emory Job Listing can be found here.